[darklajid]

Interesting that this site states

Just press shift + mute to toggle NKRO.

I understand why you would want this enabled. I'm not sure I understand the negative implications, so - what are potential reasons to _disable_ that?

[MaulingMonkey]

That is curious. Relying on an extra driver? Acting like multiple keyboards on a USB hub to work around USB protocol limitations, possibly causing complications or weirdness? </wildlyguessing>

[xorcist]

Some BIOSes doesn't work with NKRO enabled. If yours does, you can safely enable it.