[fdej]

ctypes overhead is horrendous though, at least in CPython (I don't know about PyPy). Fine if you're doing array operations on huge arrays, but not so if you have lots of small objects.

I wanted to use ctypes to wrap a C library for a recent project (for the ease of installation and development that you mention) but had to give up when it turned out to be more than 10x slower than a wrapper written in Cython, and barely faster than doing a pure Python implementation of the C library itself.