I have an impression that TypeScript (and docs) are somehow separated in its own. E.g. for Windows Store app development there are docs for C#, VB and JS. Also WinJS. So as a someone learning Node.js, it would be great to start directly with TypeScript, be it common patterns, OO, static typing or just plain syntax. Same goes for e.g. Windows app development.
What kinds of gaps of knowledge do you feel there are in using the two together?