[DSMan195276]

The content creator gets paid by the ad company for showing you the ad, the ad company gets paid if you click on it.

With that in mind, there is a net-positive outcome for the ad-company if users who aren't going to click on the ads use ad-block, because that means they don't have to pay the content creator for showing ads that nobody clicked on. They only miss possible profit if you're using ad-block but would have clicked on an ad were it presented to you, which is unlikely considering ad-block is generally opt-in. Depending on the ratio of how much they make per-click vs. how much they pay the content-creator per ad, they could definitely come-out with more money due to users using ad-block and not requiring them to pay the content creator when they wouldn't have clicked on the ad anyway.

[calbear81]

Not all ads are click based. You're thinking primarily of AdSense and a lot of retargeting ads but most ads are still bought on a CPM basis based on views. Yes, if a publisher consistently shows ads that have a low CTR (clickthrough rate), then the ad network should optimize out of displaying that ad on that site.