Another vote for ShopTalk[1]. Also Jen Simmons' The Web Ahead[2] is fantastic, and gets into some higher-level trends and concepts in tech, art and design. For my Chris Coyier overdose, I tack on Codepen Radio[3]. On the UX and design side, I love The Dirt[4] and Hustle[5]. Finally, The Businessology Show[6] does a great job covering management and leadership (focused on the agency/service world).