[icebraining]

Software Engineering Radio is pretty decent, with varied content about the topic: http://www.se-radio.net/

Not tech related, Radiotopia[1] has quite a few decent podcasts. I've been really enjoying The Allusionist[2], which is about the English language.

[1] http://www.radiotopia.fm/

[2] http://www.theallusionist.org/