[CyberDildonics]

Sean Parent would bring up the fact that given enough scale all systems end up being a network problem. If you look at the internet, you can think of it as one big system. Huge and hideously complex, its pieces are connected but not dependent.

If you can boil your software down to parts that can afford latency (even if they need throughput), you can pass messages between them. That is possibly and probably less efficient, but your macro pieces that pass well defined messages between each other can exist without adding to the complexity of the other pieces.