[M_NotableLabs]

- This is one of the reasons we have started with Glioblastoma Multiforme (grade 4 brain cancer), as it has been grown in serum free suspension cultures (the neurosphere assay) by many labs for the past decade or so. When we eventually look to move into other cancers we will need to re-engineer the process.

-Since all of the drugs are FDA approved we don't have to apply to get compassionate use as you would if you were obtaining an experimental therapy outside of a clinical trial. The approved drugs can be used at a doctor's discretion as an off label prescription within our current system. As for safety please see my response to the first comment.

-Yes we are going to be sequencing all of our tumors. The difference between our approach to this versus existing personalized medicine sequencing is that we're more interested in using biomarkers in the future once we've identified a patient population that responds to a certain drug combination.

This is our long-term goal, to use a patient's biomarkers to predict drug response that we can then validate in vitro and in vivo rather than just relying on empirically physically testing drugs on a patient's cells.