[nosuchthing]

You seem anthropomorphize "The Universe", as some God-human like creature?

Structure (and the immense variety), life, mutations, and the known universe that exist rather than infinite disorder and an entropic void seems more than just "indifferent".

[mynameisvlad]

I don't see the OP trying to anthromorphize it at all. It's merely looking at the universe as it is. If you or I, or hell, even the entire human race, suddenly ceased to exist, it wouldn't be felt even outside our planet. Mars' orbit wouldn't change, a nearby star wouldn't suddenly go supernova, etc. We are such an incredibly small part of the universe that we don't really affect anything outside our planet.