[drinian]

The SSRI-class antidepressants' efficacy also appears to be somewhat linked to genetic factors (despite their all being, in theory, quite similar in action). Zoloft seems to be the only thing besides benzodiapenes that will keep my panic disorder in remission; I chose this drug because a blood relative was already using it successfully to treat much more severe problems.

So I can't speak to its effectiveness as an antidepressant, but they can work quite well on anxiety in many cases. I am also taking fish oil supplements to see if that helps improve things further, but I can say that low-dose fish oil for a couple of months on its own wasn't enough for me. From a nootropic standpoint, it might have some benefits regardless.