[wallaceowen21]

No, Simpsons wasn't first. See the movie "Being there" with Peter Sellers - the wealthy but aged and ill king-maker in this imagined U.S. gets regular blood infusions of 'young blood'.

[ams6110]

There was also the classic "All in the Family" when Archie Bunker learns he's received blood from a black donor.

[serf]

goes back further than that! [1]

[1] : How to live forever: lessons of history http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1119261/

[gnaritas]

Vampires did it first.