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by aantix 4166 days ago
I had been feeling a little blue the past few months. I didn't want to take an anti-depressant (too heavy and too many side effects).

I read this book : http://www.amazon.com/The-Mood-Cure-Program-Emotions-Today/d...

She basically advocates for the supplements 5htp and St John's Wort taken three times a day (empty stomach ideally).

Her theory is that a lot of our depressive moods are due to nutritional deficiencies and that the amino acids that help with serotonin production are easily depleted (via drinking coffee, alcohol, aspartame, stresses, and lack of sleep).

Nonetheless, I am feeling better, and feeling like I am making incremental improvements each week. Much less anxiety.

No side effects to report (sexual, clouded brain syndrome).

St John's Wort: http://examine.com/supplements/Hypericum+perforatum/

5-HTP http://examine.com/supplements/5-HTP/

L-Tyrosene is also advocated in the book as a motivational booster (increases dopamine). It's effects feel like a strong cup of coffee.

I'm not in any way connected to this book or these supplements; just happy to share something that worked for me regarding depression and anxiety.

1 comments

Why the downvote?
I didn't downvote you but supplements are far from risk free. Also in the US you could be ingesting almost anything when you buy a supplement, thats how unregulated the industry is. you need to talk to your doc before starting any supplements. Especially if you are on medication.
Because you're effectively taking unregulated medicines with similar mechanisms to standard anti-depressants?
So because they could be dangerous, I shouldn't post the information?

I included the links to examine.com which gives a descent meta analysis of the research behind each of them. Both of them show promising research results.

Safety is never guaranteed. Certainly I don't have to spell this out for the HN audience?

Do your own research. Weigh the risks. If the safety profile is to your liking, then find a trusted supplier and ramp up slowly. Stop immediately if any undesirable effects are noticed.

>Stop immediately if any undesirable effects are noticed.

Probably not the best idea since if you are taking something that actually increases serotonin you will give yourself antidepressant discontinuation syndrome by stopping abruptly.

http://en.wikipedia.org/wiki/Antidepressant_discontinuation_...

You're exhausting to discuss with, even over the Internet. 300mg is a very normal dose. Serotonin syndrome isn't going to be induced with such conservative dosing.
....?

I never said anything about serotonin syndrome...?? ...

Furthermore, I wasn't even the original GP, so how am I "exhausting?" The only thing I said was supplements are basically unregulated (theres a good chance your bottle of St Johns Wort is actually rice powder * ) and talk to your doctor before taking supplement and before stopping supplements abruptly. Trust me, antidepressant discontinuation syndrome is complete HELL.

* http://mobile.nytimes.com/2013/11/05/science/herbal-suppleme...

not sure (wasn't me) but I have had very negative results with St John's wort. Definitely made my anxiety far worse when I tried it. Different responses... the fact that it had an effect is at least some indication that it's playing with the right systems.