[kstrauser]

My own reasons: because Django is awesome as long as you want to do everything the Django way. For example, as soon as you want to upgrade to SQLAlchemy because every other business unit is already using it, you're in for pain. You can unwire some of those low-level decisions and plug your own code it, but with all the difficulty that usually brings, what's the point of using Django in the first place?

Django was born as a CMS and it really excels there, but it's modeled as a complete end-to-end stack. That's great if you love every single component of that stack, but not so great if you'd prefer alternatives.