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by abandonliberty
4205 days ago
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A lot of this makes sense in the new deterministic model of aging. It argues that aging is not a collection of mutations, the old/popular model, but instead a programmed outcome of our genes that never experienced selective pressure. We are like a building, but the builders never know when they are done and eventually start doing counterproductive work that destroys us. Kicking in a response to injury or pathogen may cause cells to run programs that are less detrimental to our continued survival. Edit: Let me clarify that this in no way should be taken as an endorsement of the author's claims. I have proposed a possible model that would make the claims reasonable, but haven't examined them closely. There is a lot of quackery out there. |
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Recently research on very old lady showed that all of her immune cells came from just a handful of stem cells.
It made me think that the only reason we live that long is because, that's how long our immune system lives. As we grow old it becomes less and less versatile as stem cells die out and less effective as the most effective randomly die out. Then the old age diseases kick in as there's less and less competence in cleaning up this pile of bio-matter that we are.
Excising and eating a little is not because it almost kills us and therefore it makes us stronger, just because our cleaning crew was optimized for much less food and much more movement.
Stress is not good for you. When you see pair of identical twins you can tell which one lived life of more stress. He/she looks older and by various measurements is older.