I don't know what exactly you mean by that, but I'm going with no. Unconditional jumps do interact with the uops cache in recent Intel chips, but they do so by terminating the current uops cache line---which is generally desirable.
Loops can be implemented with JMPs, and it would be Very Bad if every iteration of a loop invalidated caches. (In fact, it would be Very Bad if just about anything common invalidated caches, given how important they are to modern CPU performance.)