[kmnc]

Is there anything that actually comes close to doing this and doesn't fall into the problem of "...turns into an exercise of shoehorning your data into a system that just can't accommodate it."? Sadly, from what I have seen Salesforce is probably still the best solution beyond building your own apps.

[wpaprocki]

Yeah, Salesforce might just be the best of these types of systems. But even then, it is the best-dressed clown at the circus. Unless you have a really simple business model, you should probably just build a custom app.