[girvo]

Eh, why bother when iTerm2 gives me the same splitting and tab features :)

[zachrose]

I used to have the same question, but having a remote tmux session that persists forever has turned out to be awesome.

[nknighthb]

A remote session doesn't help when you're trying to run commands on your local system.

[DonHopkins]

I helps me, because I always fat-finger Command-W close tab instead of Alt-W copy region to selection in Emacs, and it closes my tab. I can get it back when I run Emacs under screen!

[Moto7451]

iTerm2's Tmux integration (native tabs and panes backed by a tmux session) lets you have your cake and eat it too it's my standard dev flow for remote or local work. Just add -CC when firing up tmux within iTerm2.