Given the recent abundance of jQuery alternatives, that's a big assumption to make. It's always disappointing when I find some code I want to use and it has a bunch of dependencies that make it not an option.
I'm not aware of any jQuery alternatives. Most things that predate jQuery (prototype, mooTools, YUI) have long since fallen out of favor, and the 'alternatives' to jQuery are mostly API-compatible subsets (jqLite, zepto). What exactly do you mean by 'abundance of jQuery alternatives'?
I might be an edge case, but I use Dojo a lot because it's much better structured for larger JS applications than jQuery which quickly becomes a mess if you start doing a lot in JS.
That said, it does everything jQuery does, and more, and in a very nice way IMHO. If you're used to the jQuery syntax sugar, you probably don't like it, but I never liked sugar.