[seren]

Nothing is unmanageable, and it is obvious that an engineered habitat will be less "diverse" than Earth that have evolved for billions of years. Take food for example. The basics will be available anywhere in the Solar system, but you are not going to eat fresh seafood or truffle. I know that this sounds pretty trivial, but lots of what we are taking for granted on Earth will need lots of careful planning and execution to get elsewhere.