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by dbbolton 4288 days ago
I explicitly stated that I was not advocating drug use. What I am advocating, if you would actually bother read my comments, was that the farmers' dose and dose frequency are pushing the therapeutic window (i.e. it nears toxicity). Regularly taking a therapeutic-level dose of hydrocodone would not push that window.

If you think repeatedly taking extremely high doses of Tramadol is somehow safer than small doses of hydrocodone, then you're unbelievably ignorant.

As a side note, hydrocodone is one of the least potent mu-opioid antagonists, but it is more potent than Tramadol. That is the only reason I mentioned it by name.

And I take no stock in governmental drug laws with regard to pharmacology, so your mention of it being removed from medical use in a handful of countries means nothing to me.