[Gatsky]

Not having to deal with all the complexities of analysing short read sequence data would be fantastic, I hope they get the accuracy a bit better. At the moment current sequencing technologies are great at detecting mutations but struggle with changes in gene number, gene fusions and large structural variation at the kilobase or more scale. Hopefully long read tech will open up this aspect of genomic information to greater scrutiny.

Having said that, for cancer genomics, the vast majority of archival tumour tissue in the world is stored in a way that auto-fragments the DNA, so being able to do long reads won't actually help...