With respect to psychedelics, they actually do affect your brain. You'd be hard-pressed to tease apart what portion of the outcome was unaffected by the drug when claiming that the results were all due to the Placebo Effect.
That's true, but there's no chance to have a control group. No one having an acid trip can possibly compare his subjective experience to someone who's taken a sugar pill. And without control groups and other strict controls, human studies are next to useless.
The above means that the Placebo Effect cannot be realistically guarded against or dismissed.
The above means that the Placebo Effect cannot be realistically guarded against or dismissed.