[pionar]

> drugs which I'm familiar with and have studied extensively through literature and some self experimentation.

Sorry, a sample size of one does not make a drug "safe". The fact is, there's no such thing as a safe drug, as everyone's body reacts differently to each one.

> although none are as destructive as alcohol.

Really? Are you really saying that heroin, which is one of the most addictive drugs in the world, is not as destructive as alcohol? While there are more alcoholics than horse heads, that's because there's more people that drink alcohol as a whole. Are there any studies for the ratio of abusers/users for heroin and alcohol?

> Nicotine is another extremely addictive substance.

The difference being, nicotine's psychoactive effects are minor compared to hard drugs. People don't die from a nicotine overdose.

[duncanawoods]

>> Are you really saying that heroin, which is one of the >> most addictive drugs in the world, is not as destructive >> as alcohol?

In terms of the chemicals themselves, this is generally considered to be true.

The risks of heroin are in unsanitary IV injections, OD from impure/variable product and the lifestyle of a street addict. Aside from addiction, similar pharmaceutical preparations of opiates (codeine, morphine etc.) is widespread.

However with alcohol, we have the short-term effect of injury and 100s of longer term conditions including cirrhosis and alcoholic dementia. It may be less addictive but the irreversible physical damage of the substance itself is much higher. AFAIK there is no medical benefit to high levels of blood-alcohol and only harm.

In terms of societal harms, we get extensive petty theft of heroin addicts but UK A&E and jail cells are dominated by the violence and injury fuelled by alcohol use.

>> People don't die from a nicotine overdose.

The number of smoking related deaths is truly shocking so I wouldn't trivialise it. Recovered heroin addicts often report breaking smoking addiction to be even harder.

[Xylakant]

>> although none are as destructive as alcohol.

> Really? Are you really saying that heroin, which is one of the most addictive drugs in the world, is not as destructive as alcohol? While there are more alcoholics than horse heads, that's because there's more people that drink alcohol as a whole. Are there any studies for the ratio of abusers/users for heroin and alcohol?

Your parent poster is right here. Heroin (and opiates in general) are pretty safe substances in pure form. That's one of the reasons that opiates are still among the preferred potent pain killers in hospitals: Little side effects, extremely potent, a very big window between effective dose and overdose. If you're in really bad pain, at least in germany, you'll get a morphine drip.

The "drug" effects you see in documentaries about drug often are no effects of the drug itself, rather than the stuff that the dealers mix the drug with, the use of unclean needles (infections and stuff) and the conditions that the addicts live in. Overdoses are typically either on purpose or most of the time the result of extreme variations in the potency of the drug. There was (or still is) a medical trial that gave clean, controlled heroin to hard addicts in Hamburg, Germany and from what I read that trial was very successful: The people in the trial were basically able to function in a normal day live with a regular job. Obviously no driving, no handling heavy machinery, but otherwise a major step up from living on the street.

[JoeAltmaier]

But all those side effects are the direct result of using morphine, right? Splitting hairs to say 'so morphine is safe'. It like 'this knife is safe; its just the cuts that hurt you'.

Still, alcohol is more destructive overall since so many more people abuse it.

[tych0]

No, those are side effects of using morphine (heroin) that you got from a shady drug dealer network, instead of something more pure from a regulated corner store.

[win_ini]

> The difference being, nicotine's psychoactive effects are minor compared to hard drugs. People don't die from a nicotine overdose.

Correction- People have died from Nicotine - and with e-cigs there;s concern that it may become more common:

http://en.wikipedia.org/wiki/Nicotine_poisoning

"The U.S. Centers for Disease Control and Prevention warned in report released today that the number of phone calls to U.S. poison control centers related to e-cigarette use has increased from just one call per month on average in 2010 to nearly 200 calls per month in early 2014." http://abcnews.go.com/blogs/health/2014/04/03/e-cigarette-po...

[elsjaako]

Nicotine overdose would be more common if people injected it. Smoking heroin isn't actually that dangerous (though admittedly, more dangerous short term than smoking tobacco). Why don't people smoke it then? Because the illegality makes it really expensive, and injecting is more effective.