[ANTSANTS]

>SNES had the familiar ABXY, but mirrored with AX on the right.

Those of us that grew up with Nintendo consoles would say that B on the left of A is the natural order of things ;)

>Meaning, one console used the bottom button for yes and the one on its right for no (Megadrive)

Actually, almost every Megadrive game I've played lets you use both A and C for accept in menus, so you could use whichever orientation you were more comfortable with.