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by zspade 4323 days ago
Really, this is an incredible assertion that goes against all recent research results, and therefore requires sunbstantial evidence or citation thereof. I believe his source would be the author John McDougall, who is pretty much the only person you can find pushing this... 'Hypothesis' might be a strong word. McDougall goes as far as to say Sugar is less fattening thank Olive oil. The reason he is so anti-fat looks to be a strong support for movement toward a Vegan diet. Spreading misinformation such as this is a huge diservice to vegans though, and would likely only lead to higher instances of obesity and metabolic diseases for anyone unfortunate enough to buy into it.
1 comments

What experiments are you talking about? It is very well established that human lipogenesis from sugar is rare. You have to eat a totally fat free diet and push the sugar intake to hundreds of grams to make it happen at all. A human's adipose fat is simply stored dietary fat. Plentiful sugar intake will suppress fat burning and cause all dietary fat to be stored, so obviously loading up on sugar will usually make you a lard-ass. Just somewhat less so than gorging on fat. It should be noted that this state of affairs is not true in animal models. Rats very efficiently form body fat from sugar, for example.
Frankly, almost every single word in the stated bears no relevance to the reality. Glucose role in lipogenesis is so well known that I won't bother going past the most obvious source:

«Lipogenesis is the process by which acetyl-CoA is converted to fatty acids. The former is an intermediate stage in metabolism of simple sugars, such as glucose, a source of energy of living organisms. Through lipogenesis and subsequent triglyceride synthesis, the energy can be efficiently stored in the form of fats».

https://en.wikipedia.org/wiki/Lipogenesis

Yes, human adipose tissue and the liver perform lipogensis. I don't know where I said otherwise. The point is it happens at a very negligible rate in humans on any realistic diet. The process can be ramped up if you go on a truly fat free diet, but that's almost impossible in practice. You can take a fat sample from a human and profile almost exactly what fatty things they usually eat, because stored human body fat is pretty much entirely just dietary fats stored away.