[mattyfo]

An HTML/CSS prototyping framework that is dead simple for designers to use. They would only write the code in an easy to organize way (layouts and snippets) and the tool would take care of building everything, live reloads, creating documentation from comments, collecting feedback from stakeholders, and serving it up.

I've been wireframing for a while and have yet to reach a solution I really like.

[Lichine]

Not quite there yet, and might not be quite what you want, but here: https://github.com/AndersSchmidtHansen/Kaidan :-)