[marshallhaas]

Agreed, San Francisco is probably the worst place to be if you want to bootstrap.

[rjurney]

I don't think so. There are so many early adopter, visionary customers here you can sign up on spec to pay you to develop your product.

[vonmoltke]

Assuming your product appeals to the type of consumers or businesses that inhabit San Francisco.

[rjurney]

What kind of businesses aren't in the Bay Area that you'd want to target?

[kasey_junk]

Off the top of my head: large banks, insurance companies, automotive, military contracting, commodity agriculture & energy.

[Edit] Actually, this made me think, what precisely is in the bay area that I'd want to target. The obvious answer is companies whose major priorities are VC and/or other acquisition events and the ecosystem they create.

[brianwawok]

I would take SF over Antarctica.