[3rd3]

How would one go about destroying someone’s political career?

[dkrich]

See Grover Norquist. He approached congressional members of both parties with a pledge to never raise taxes. If a member refused to sign or signed and violated the pledge, his group would go into the local elections in that person's constituency and heavily fund their opponents.

If you aren't familiar with this, you might be surprised to see who signed it.

[CapitalistCartr]

1) Support their opponent in the primary with enough to unseat them.

2) Send private dectectives to follow them.

3) Dig up dirt from their past.

[troygoode]

By financing their opponent in the primaries.