[mquandalle]

The problem is that most current jQuery plugins modify the DOM. If someone want to use a jQuery carousel, the plugin will add arrows buttons and page indicators in the DOM. Then if the template engine updates one of the carousel slide, these nodes will be removed and the plugin will be broken.

[Yahivin]

My advice for that kind of application would be to have a piecemeal approach. Use Hamlet for some templates on your page, and jQuery plugins for others. I hope it's modular enough to use as little or as much as you like.