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by dmm 4432 days ago
That's what I thought but then the article says this:

"""

The Y has been stable for the past 25 million years, scientists say. And a major reason is that many of its remaining genes are crucial to the survival of all humans, going far beyond sex determination. There are genes that affect protein synthesis, how active a gene is, and others that splice RNA segments together. They are found in the heart, the blood, the lungs, and other tissues throughout the body. “These are powerful players in the central command room of cells,” says David Page

"""

2 comments

I guess it depends a bit on what genetic regions we're talking about but to my knowledge since the Y contains so few genes it's not surprising that almost none of them changed for a long time. It's already very stripped-down. I'm far less sure about non-coding regions though, I'd have to check up on that.

From what I can tell the text doesn't contain a lot of new or surprising information, but it does present it in a misleading way.

It's clear that sexual dimorphism in humans is profound in some respects and superficial in others. Since the Y chromosome regulates sexual development, and since males do get some metabolic modifications, saying the Y influences protein synthesis in vital tissues is mostly a truism.

Saying that for example autoimmune diseases with lopsided sex distributions are not connected to sex determination is a fruitless semantics game disconnected from the actual science. To be fair, it's not any more sensationalist than the "rotting Y chromosome" spiel which has been in the press earlier, but all of this is really more a testament to all the things that are wrong with science reporting (and the scientists who enable it) than anything else.

Well that's the question - if it's "crucial to the survival", then how do ~50% of all humans survive without it?

The article does makes a point that unimportant genes have been eliminated from the Y. However, if the remaining genes and relevant proteins are beneficial (as opposed to mandatory), then it would still make sense in the [very] long run that those genes would migrate to some other chromosome, be beneficial also for female homo sapiens, and then get eliminated out of the Y as redundant there (since they'd be somewhere else for both genders already)