I don't think he's referring to 3rd world poverty. He's talking to the hundreds of thousands of people who work at Google or Facebook or PayPal vs the handful of people who try and build the next great thing.
Regardless, it's still an incredibly arrogant thing to say. The implication is that there this class of entrepreneurs who are better than the 9-5ers. Honestly, get over yourself. (And I say this as an entrepreneur who can't stand to work a 9-5.)
And next great thing? Seriously? Next great thing is curing cancer not a real estate site.
And next great thing? Seriously? Next great thing is curing cancer not a real estate site.