[cornholio]

As if the world would need another browser plugin to play little boxed animations. No disrespect to the original author intended, but no.

[lmm]

Well with adobe dropping flash, microsoft dropping silverlight, and browsers blocking java applets, there aren't actually any good options at present.

[lucaspiller]

Unity 5 will support WebGL; no plugins needed.

[LukeB_UK]

Javascript.

[Houshalter]

Probably not, but to be fair, the video of it does look pretty smooth.