[copter]

Marijuana is great if you are going to do some UI stuff and gonna work on light topics on the Front-End. The output will be more aesthetic and more artsy.

But hey! Let's don't fool ourselves here. If you are going to implement some back-end stuff and business functionality - don't code high. Thinking about abstraction levels, algorithms, core functionality, in some point you will absolutely feel like there is some sort of barrier in your brain avoiding you to think 'further'. This causes a distraction and you will have to start thinking from scratch again.

About other natural stuff like shrooms (and partially LSD) - if you get your good mind after having the first intense kick, your brain might become crystal clear and you can be absolutely productive. Coke might also work, but that's too expensive. Stay away from the rest.

Steve Jobs was on LSD when he was inventing Apple in his Garage.