[logfromblammo]

If you are an amateur experimenter, and require a human test subject, self-experimentation may be your only remotely ethical option.

There is also the added advantage that you also know whether the test subject is complying with the experimental protocols. The disadvantage is that the person running the experiment on you is an amateur that may not necessarily be aware if the experiment is harmful.

Given that many physicians can't be certain of the results when they prescribe treatments and medications, I figure that if they can roll the dice like that without even having a stake in the outcome, people who take greater risks for greater payouts are not crazy. They are just less risk-averse.