[logfromblammo]

Remember, the screen reader reads the entire screen. If you don't provide some thought to the user experience, people using screen readers can still use your site full of menus and sidebars and advertisements and article pagination, but they will probably be very frustrated by it, trying to find the content that they actually want to hear.

Imagine the person who essentially has to look at the world through a drinking straw, and try not to be a dick to him by adding clutter. Copying your content into pages with simple navigation--without frames or scripts, possibly with tree-hierarchy outlines and prev-next links--is not required, but is definitely a nice gesture.