[sorbits]

As I said, generating a Makefile (i.e. the dependency graph) from Python would be fine, which conceptually sounds like what SCons do (from your comment).

But look at the build file example on the fabricate page, it is a user supplied build file with a build function which calls a compile function which loops over sources. Having the fabricate system take input like that and do parallel execution is as hard as solving the halting problem.