Yes, absolutely! Our first principle for Wagtail is that it should in no way impede design decisions.
LESS is (currently) used for the admin UI, and the compiler / compressor is available to the front-end if you want it, but you can easily plug in your own compilers or use plain CSS if you prefer.
LESS is (currently) used for the admin UI, and the compiler / compressor is available to the front-end if you want it, but you can easily plug in your own compilers or use plain CSS if you prefer.