Check us out at http://nutshell.com — we've got a one-click import tool from Highrise. We're an established, profitable company focused on CRM with gorgeous UI.
We use Capsule + Streak. We're big fans of streak, but it's a baby CRM perfect for pipelines... we use Capsule to manage all of the other stuff. (Who talked to whom, etc.)
We've also got an easy migration tool for any existing Highrise users: http://close.io/highrise and a solid REST API http://developer.close.io/