Some of my favorite LPs have come from LtMkilla (Dead Space and the ill-fated Bioshock LPs come to mind). His humor probably isn't for everybody (whose is?), but I love his videos.
If we're highlighting great LPs, I'll have to throw in a recommendation for ChipCheezum's LPs of the Metal Gear Solid games. The humour is spot on, and the games themselves are covered in exhaustive detail. His LPs of Mega Man Legends and the Uncharted series are great too.