[Refefer]

Perhaps it's simply personal preference, but I do find that limiting my mouse usage has resulted in real, tangible gains. I don't know how feasible that is in GUI-first operating systems like OS X, though.

[lunixbochs]

Check out Alfred 2, Shortcat, Slate (https://github.com/lunixbochs/reslate). You don't need the mouse as much as you might think.