[mwhite]

Looks like it's pretty robust: http://www.geoalchemy.org/tutorial.html

[psgibbs]

It is, though if you're using PostGIS, I'd recommend GeoAlchemy2[1], which ties into SQLAlchemy a bit more naturally (because they get rid of support for all other engines). Also, seems to be more actively developed/maintained.

[1] https://geoalchemy-2.readthedocs.org/en/latest/