[hershel]

Since people here talk about the difference of e-cigs and cigarettes , i.e. the lack of effects on MAOI, have anybody tried any juice that claims to have that effect on MAOI, for example "aroma ejuice" ?

How were the results for you ? And does anybody know about research or regulation of this types of ejuices ?

And since those same MAOI affecting compounds(probably beta carbolates) found in tobacco ,are found in brewed coffee, kinds of seasoning, grilled foods and other stuff, have anybody noticed a combination of vaping and some food more effective ?

[praxeologist]

Beta-carboline MAOI's were originally hypothesized to be what is important for those who feel something is missing with nicotine-only eliquid. After 3 years of working on this, I can tell you that this is not true. What's important is the other "minor tobacco alkaloids" like anatabine, anabasine, myosimine, etc.

Beta-carboline MAOI's, like the minor alkaloids, do have a potentiating effect with nicotine and therefore increase satisfaction or the potential for addiction; however, these MAOI's are pyrosynthesized (created by burning) 20-40x. This means that these MAOI's are not a significant component of a WTA eliquid or non-burned tobacco like the snus many people turn to for the "something missing".

[gwern]

> What's important is the other "minor tobacco alkaloids" like anatabine, anabasine, myosimine, etc.

Interesting. Could you provide more info about this?