[unoti]

It seems possible to me. I know Sucralose is actually made from sugar as a starting point, then they chemically alter it.

As for can it be harmful, maybe so:

"A Duke University study[35] funded by the Sugar Association found evidence that doses of Splenda of between 100 and 1000 mg/kg, containing sucralose at 1.1 to 11 mg/kg (compare to the FDA Acceptable Daily Intake of 5 mg/kg), reduced the amount of fecal microflora in rats by up to 50%, increased the pH level in the intestines, contributed to increases in body weight, and increased levels of P-glycoprotein (P-gp).[36] These effects have not been reported in humans."

http://en.wikipedia.org/wiki/Sucralose#Other_potential_effec...