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by ygra 4658 days ago
Remember Windows NT which ran on PowerPC, MIPS and Alpha. They even ran x86 binaries on Alpha which were not only emulated but also translated for later runs [1].

Admittedly, all the other architectures Windows supported apart from x86 were added and later dropped again, so it were more sidesteps instead of transitions.

[1] http://en.wikipedia.org/wiki/FX!32