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by jacques_chester 4687 days ago
The effect of PEDs is also mediated by genetics. Take the grand-daddy of PEDs, testosterone.

Some people respond better to it than others. Some people have more testosterone receptors. Some people aromatise more of it into DHT or estrogen than others. Some people have more SHBG, a protein which disables sex hormones.

Variability in response happens for every PED. The introduction of PEDs has not removed selection, it's just changed the selection function.