[callmecosmas]

I think the main difference is that SLIME is for Common Lisp and Geiser is for Guile/Racket. More than that, I don't know enough about SLIME to say.

[msl]

SLIME can actually be made to work with many different lisps, including several Scheme implementations. I use it (actually, SLIMV, which is the same thing, only for VIM) with Chicken Scheme.

[cjh_]

Thank you for mentioning SLIMV, I am a schemer-in-training and was 'afraid' I would have to abandon my beloved vim.

[momo-reina]

Ah that might be it, I'm also quite ignorant of Scheme and thought that most Schemes would be able to run without problems; seems like only Scheme48, MITScheme and Kawa are supported.