Except it takes about 5 seconds for sucrase in your small intestine to hydrolyze sugar into exactly the same substances present in HFCS. So it doesn't matter. At all.
Most HFCS in use today is a mixture of 45% glucose / 55% fructose. Sucrose is 1 glucose molecule and 1 fructose molecule bonded together. If fructose is really the 'bad' thing here, then HFCS has more of it.