[whafro]

Are you doing this manually? I make solid use of DNSimple's ALIAS record type, which is also supported by Route 53, but DNSimple says they don't support AXFRs (http://support.dnsimple.com/articles/master-slave-support).

[yesimahuman]

Honestly, I'm not a DNS pro, but I added more nameservers in our registrar to point to R53 nameservers, then setup R53 to point to our Heroku app w/ alias support by following this guide: https://devcenter.heroku.com/articles/route-53