[philfreo]

If you're someone who actually enjoys using LastPass, I don't really know what to say.

The UX (and design) of 1Password is way better.

But another important reason is that LastPass is a central service where you have to (at least somewhat) trust them to not screw up since all your (encrypted) passwords are on their servers. With 1Password there is no such mandatory central service.

I'd say the only reason to use LastPass is if you're cheap, or if password-sharing is a daily exercise for you.

[philwebster]

Another reason to use LastPass is if you use multiple computers. (I use 5+ computers at work in tech support and 2+ at home.) Using 1Password would require that I install the desktop application on all of these computers, whereas with LastPass all you need is the Chrome extension.