It is large, but doesn't use any streaming or piping. As for remote services, just a bunch of remote APIs, and they work fine.
With the changes to streams in 0.10, I can understand it having some issues. That slipped my mind... but I don't do much streaming so I just assumed it worked.
Regarding bugs, there are too many to list, just see the tracker and spend some time browsing through them https://github.com/joyent/node/issues?direction=desc&pag... I'm fairly sure you can find pretty much anything.
I'm considering removing all the npm modules from my project and go raw, since most of the obscure bugs are in the ecosystem anyway.
Somehow I missed domains are also in 0.8, thanks!